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Cleveland Clinic opening pathogens research center in South Florida

Cleveland Clinic is establishing the Center for Global and Emerging Pathogens Research to broaden understanding of emerging pathogens—ranging from Zika virus to SARS-CoV-2 (which causes COVID-19)—and to expedite critically needed treatments and vaccines.

Serpil Erzurum, M.D., is chair of Cleveland Clinic’s Lerner Research Institute

The new center has been in the planning stages for 18 months and will span Cleveland Clinic’s Lerner Research Institute and the soon-to-open Cleveland Clinic Florida Research and Innovations Center in Port St. Lucie, Florida. A team of renowned experts will lead the center to advance research toward diseases such as COVID-19, highly pathogenic influenza, Dengue fever, AIDS and Zika virus-related conditions.

“Novel pathogens to which we have little or no immunity are a tremendous risk to global health,” said Serpil Erzurum, M.D., chair of the Lerner Research Institute. “We have some of the world’s top research experts in virology, immunology, genomics, population health and drug discovery coming together to form a team approach on infectious disease research.”

Leveraging Cleveland Clinic’s robust research infrastructure, the center’s researchers will uncover the scientific mechanisms of how SARS-Cov-2 and other pathogens cause disease. In addition, the researchers will closely collaborate with the newly established Cleveland Clinic BioRepository to have access to patient tissues and electronic medical record data through a large-scale secure database.  The new center will be supported in large part by philanthropy.

The research team will collaborate with the drug developers at Lerner Research Institute’s Center for Therapeutics Discovery to rapidly translate research findings into life-saving therapies and experts in the Populations Health Research Center to understand socioeconomic factors that affect risk of infection and poor outcomes.

In light of the global pandemic and in anticipation of the new center’s opening, Cleveland Clinic is ramping up research related to COVID-19. A research registry of nearly 10,000 patients is collecting data from patients tested for COVID-19 at Cleveland Clinic and there are plans to integrate the data with electronic medical records. The researchers will mine the data to inform other studies, such as the development of tools to predict risk and outcomes in patients.

Cleveland Clinic researchers published findings last month on a network-based prediction model using artificial intelligence to identify targets for drug repurposing in coronaviruses and COVID-19 specifically. Based on their findings, they prioritized 16 drugs and three drug combinations as potential treatments.

Other projects are uncovering how SARS-Cov-2 enters human cells, replicates and causes disease. A clinical trials committee has been formed to identify and prioritize the most promising therapies for mild to severe disease.

Joseph Iannotti, M.D., Ph.D., Cleveland Clinic Florida’s Chief of Staff and Chief Academic and Innovation Officer

In partnership with Cleveland Clinic Florida, the new center will also conduct research at the Florida Research and Innovation Center building, a state-of-the-art research facility, complete with a biosafety level 3 laboratory anticipated to open in summer 2020. The facility features 107,000-square feet of high-tech laboratory and office space situated on eight acres of land.

“The new Florida Research and Innovation Center will complement and expand clinical research underway throughout ClevelandClinic,” said Joseph Iannotti, M.D., Ph.D., Cleveland Clinic Florida’s Chief of Staff and Chief Academic and Innovation Officer. “Our vision is to create a research institute dedicated to taking bench discoveries and creating leading-edge diagnostics, preventatives and treatments for infectious disease, oncology and other pressing healthcare problems.”

“This new center will span our global healthcare system,” said James Young, M.D., Chief Academic Officer at Cleveland Clinic. “It will provide critical technologies and resources, empowering our clinicians and scientists to understand biological pathways and develop new treatments against the novel coronavirus and other dangerous pathogens.”

 

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Drew Limsky

Drew Limsky

Editor-in-Chief

BIOGRAPHY

Drew Limsky joined Lifestyle Media Group in August 2020 as Editor-in-Chief of South Florida Business & Wealth. His first issue of SFBW, October 2020, heralded a reimagined structure, with new content categories and a slew of fresh visual themes. “As sort of a cross between Forbes and Robb Report, with a dash of GQ and Vogue,” Limsky says, “SFBW reflects South Florida’s increasingly sophisticated and dynamic business and cultural landscape.”

Limsky, an avid traveler, swimmer and film buff who holds a law degree and Ph.D. from New York University, likes to say, “I’m a doctor, but I can’t operate—except on your brand.” He wrote his dissertation on the nonfiction work of Joan Didion. Prior to that, Limsky received his B.A. in English, summa cum laude, from Emory University and earned his M.A. in literature at American University in connection with a Masters Scholar Award fellowship.

Limsky came to SFBW at the apex of a storied career in journalism and publishing that includes six previous lead editorial roles, including for some of the world’s best-known brands. He served as global editor-in-chief of Lexus magazine, founding editor-in-chief of custom lifestyle magazines for Cadillac and Holland America Line, and was the founding editor-in-chief of Modern Luxury Interiors South Florida. He also was the executive editor for B2B magazines for Acura and Honda Financial Services, and he served as travel editor for Conde Nast. Magazines under Limsky’s editorship have garnered more than 75 industry awards.

He has also written for many of the country’s top newspapers and magazines, including The New York Times, Washington Post, Los Angeles Times, Miami Herald, Boston Globe, USA Today, Worth, Robb Report, Afar, Time Out New York, National Geographic Traveler, Men’s Journal, Ritz-Carlton, Elite Traveler, Florida Design, Metropolis and Architectural Digest Mexico. His other clients have included Four Seasons, Acqualina Resort & Residences, Yahoo!, American Airlines, Wynn, Douglas Elliman and Corcoran. As an adjunct assistant professor, Limsky has taught journalism, film and creative writing at the City University of New York, Pace University, American University and other colleges.